Tuesday, May 16, 2023

Reasons and Outcome of Patients after Permanent Transfer from Peritoneal Dialysis to Hemodialysis: A Review of 16 years of Experience in Senegal



 

Abstract

Introduction: Peritoneal dialysis (PD) and haemodialysis (HD) are two complementary and non-competitive renal replacement therapy (RRT). A patient can be transferred from one technique to the other. The objective of this study was to assess the reasons for transferring patients from PD to HD and to follow their outcome.
Patients and Methods: This is a 16-year descriptive and analytical retrospective study (March 1, 2004 - August 31, 2020) conducted at the PD unit of the Aristide Le Dantec University Hospital in Dakar. Were included, patients on PD for at least 30 days, over 18 years of age and permanently transferred to HD. The probability of survival for any duration of post-transfer follow-up was estimated by the Kaplan-Meier method.
Results: The analysis covered 98 out of 113 cases. The mean age of the patients was 45.2 ± 14.09 years at the initiation of PD and 47 ± 13.91 years at the time of transfer, with a sex ratio of 0.66. The mean duration in PD was 19.9 ± 17.25 months [range, 1.0-90.0 months]. The transfer to HD concerned 73.5% of patients in the first two years. The reasons for transfer were mainly associated with infection (82.7%), mechanical complications (23.5%), social reasons (12.2%) and inadequate dialysis (6.1%). It was programmed in 11.4% of cases and 6% of patients had a permanent approach. At the endpoint date, the mean duration in hemodialysis was 43.3 months with 42.8% of patients still in HD. There was a kidney transplant patient; a return to PD. Mortality was 34.6%. The mean HD survival was 126 months. There was a statistically significant relationship between infection as a reason for transfer and mortality (p = 0.047).
Conclusion: The main reasons for transferring PD to hemodialysis identified in the literature are found in our context. This transfer must be anticipated to reduce morbidity and mortality.

Read more about this article: https://lupinepublishers.com/urology-nephrology-journal/fulltext/reasons-and-outcome-of-patients-after-permanent-transfer-from-peritoneal-dialysis-to-hemodialysis-a-review-of-16-years-of-experience-in-senegal.ID.000161.php

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