Showing posts with label Journal of Urology. Show all posts
Showing posts with label Journal of Urology. Show all posts

Monday, August 28, 2023

Evaluation of Buccal Mucosal Graft Urethroplasty for The Treatment of Female Urethral Strictures- A Single Centre Experience



 

Abstract

Introduction: Female urethral stricture is a highly under-reported and underdiagnosed condition encountered by the reconstructive urologist. Urethral dilatation is often performed with urethroplasty offered in select cases. In the present study, we describe our results in a series of women surgically treated for female urethral stricture disease using a suprameatal approach with a buccal mucosal graft dorsal on lay technique.
Materials and Methods: All females diagnosed of urethral stricture who underwent buccal mucosal graft urethroplasty from January 2015 to January 2020 were evaluated retrospectively. Intraoperative and postoperative parameters were assessed.
Results: A total of 14 female patients underwent buccal mucosal urethroplasty were evaluated. The mean age of the patients was 49.5 years ranging from 35 to 64 years. Mean preoperative maximum flow rate [Qmax] on uroflometry was 6.5 ml/second and the mean residual urine 156 ml. All patients underwent uneventful buccal mucosal graft dorsal on lay technique. At 3 months follow up, the mean Qmax was 23.2 ml/second with mean residual urine of 14 ml. A Self-reporting satisfaction scores using the Patient Global Impression of Improvement showed that seven patients scored 1 (very much better), four scored 2 (much better), two patients scored 3 (a little better), and one scored 4 (no change) none of the patients scored a 5 (worse).No recurrence was noted.
Conclusion: Buccal mucosal graft urethroplasty is a feasible surgery for female urethral strictures with minimal short term complications.

 

Read more about this article: https://lupinepublishers.com/urology-nephrology-journal/fulltext/evaluation-of-buccal-mucosal-graft-urethroplasty-for-the-treatment-of-female-urethral-strictures-a-single-centre-experience.ID.000163.php

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Sunday, February 26, 2023

Swathed Ureter, an Enigma in Diagnosis- A Pictorial Essay

  Abstract

This pictorial essay is an educational article aiming to provide both textual and visual portrayals consisting of a collection of images and texts on an important issue by reviewing and extrinsic encasing pathology of the ureter to provide a guide to those who are involved in diagnostic intervention. While considering diseases of the urinary system, physicians mainly focus on the kidneys and the bladder. Only scant attention is paid to the ureters. Most of the UTO due to calculi are readily identifiable whereas many cases of ureteric exterior encasement are frequently missed from early detection even by experienced clinicians and radiologists. Failure in recognition of the encasement of ureters and its causes may lead to mistaken diagnosis with resultant inappropriate management. However, problems with the ureters can adversely affect the functioning of the kidneys and could even be lethal. In this article we focus only ‘encasement of ureters’ with a few common examples and salient signs that help in the diagnosis.

Read more about this article: https://lupinepublishers.com/urology-nephrology-journal/fulltext/swathed-ureter-an-enigma-in-diagnosis-a-pictorial-essay.ID.000158.php

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Sunday, January 29, 2023

Lasers in Urology – what has Survived of our Research Starting 1970*


 

Short Communication

In 1970 I started to investigate the Laser-Technology for urologic surgery together with H. Müßiggang. First of all, it was to check the interacting of the different lasers with biological tissue. The result you can gather from the Figure 1 Decisive are the two factors: absorption and scattering of light into the tissue. The strong light absorption of the CO2 – laser leads to an excellent incision effect with low edema reaction. The light of the is mainly absorbed in the tissue by hemoglobin and pigment colorings and therefore suitable for the destruction of highly vascularized tumors or malformations. For achieving greater volume effects, - necessary for destruction of solid tumors, bilharzial bladder-lesions and inflamed areas in interstitial cystitis, - the Nd:YAG – laser was used by us since 1976 (Figure 2). Presupposed for the clinical application of lasers was the developing of a quartz glass fiber transmission system by Nath, a physicist from the Neuherberg Laser Labor (1973) and the developing of a special cystoscope insert, designed by my working-group (Staehler, Frank et al.) and constructed by the Storz Compagny/Tuttlingen/Germany (Figure 3). The next steps were the laser induced shock wave lithotripsy, developed between 1978 to 1986 (Munich/Lübeck) and the photodynamic procedures for early tumor diagnosis (Figures 5a & 5b).

Read more about this article: https://lupinepublishers.com/urology-nephrology-journal/fulltext/lasers-in-urology-what-has-survived-of-our-research-starting-1970.ID.000157.php

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Monday, November 28, 2022

Robot-Assisted Radical Prostatectomy our Technique Description



 

Abstract

Objective: To describe step-by-step technique in Robot Assisted Radical Prostatectomy of our transperitoneal posterioranterior technique for prostatic dissection with preservation of the endopelvic fascia, preservation of the puboprostatic ligaments and dorsal venous complex.

Materials and Methods: Description of our surgical technique over 80 patients who underwent RARP and the characteristics group from 2016 to 2019 excluding the rest of cases who went to different surgical approach and technique for robot-assisted radical prostatectomy.

Results: The mean age was 63 years old, 7% of patients were overweight and 7.5% had obesity. The mean pre-operative prostate volume was 42.620 cc, mean prostatic specific antigen (PSA) of 10.414.8 ng/dl. The mean console time was 198±47. The surgical margins were positive in 13.75% of the patients. Complications were recorded in the peri-operative period, five (6.2%) Clavien-Dindo I and six (7.5%) Clavien-Dindo II.

Conclusions: After 8 years of experience in our center we have modified our technique of robot assisted radical prostatectomy, improving our results, following different worldwide concepts in the prostatic dissection. Even if necessary, to increase the number of cases we have find an easier way to reproduce with acceptable results.

 

Read more about this article: https://lupinepublishers.com/urology-nephrology-journal/fulltext/robot-assisted-radical-prostatectomy-our-technique-description.ID.000153.php

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Wednesday, May 22, 2019

Lupine publishers-Journal of Urology



End Stage Renal Disease impacts the lives of over 725,000 Americans and their families. In 1972, despite the cost of supporting a rapidly growing chronic condition at the time, the United States initiated a system whereby everyone would be treated that qualifies for social security benefits, after a waiting period of three years (Medicare Secondary Payer was slowly extended over the years to 36 months after diagnosis as it currently stands), regardless of age, providing the platform for the debate of a potential nationalized health care system that currently seems to be in a period of uncertainty. However, over three decades through significant consolidation, the treatment of dialysis via two large provider chains (one fully integrated) have directed patients to hemodialysis in the out-patient setting without considering the technological or clinical benefits of home hemodialysis or peritoneal dialysis.



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Wednesday, May 8, 2019

Lupine publishers-Journal of Urology & Nephrology



Doxorubicin is a hydrophilic anticancer drug. Due to hydrophilicity, it’s difficult to encapsulate in a hydrophobic core of nanomicelles. The main purpose of this study was to develop a hydrophobic ion paring complex (HIP) of doxorubicin using hydrophobic retinoic acid (Vitamin A). The resultant hydrophobic (DOX-RA) complex was utilized to prepare drug-loaded nanomicelles by co-precipitation method with penta block copolymer. Nanomicelles (DOX-RA/PBNM), was prepared by evaporation rehydration technique. DOX-RA complex was analyzed by H-NMR and FTIR. The nanomicelles were analyzed for size and zeta potential using dynamic light scattering (DLS) as well as transmission electron microscopy (TEM). The FT-IR and the H-NMR analyses confirmed the structures of the DOX-RA complex. Mean nanomicellar sizes were 25.5nm ± 5.00nm, and ζ-potential was approximately zero. H-NMR and FTIR analysis done on DOX-RA indicate peaks characteristic of both doxorubicin and retinoic Acid. This confirmed successful complex formation. Transmission electron microscopy (TEM) analysis revealed round shaped morphology and sizes similar to DLS results. In vitro release studies revealed that pentablock nanomicelles released Doxorubicin at a slow first order rate in phosphate buffer solution (PBS) at pH 7.4 compared to pH 5.5 and pH 4.0. Confocal microscopy analysis with DOX-RA/ PBNM indicated that pentablock nanomicelles were efficiently taken into prostate cancer (PC3) cells and doxorubicin was efficiently released from the nanomicelles into the cells. In addition, cell proliferation assay showed that nanomicelles ferried adequate amounts of Doxorubicin into PC-3 cells and inhibited cell growth significantly. Results confirm that DOX-RA complex facilitated the encapsulation of doxorubicin within nanomicelles increasing DOX intracellular concentration.



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Tuesday, April 9, 2019

Lupine Publishers-Urology open access journals



Tumor lysis syndrome (TLS) is an oncologic emergency that can occur spontaneously or triggered by cancer treatment. This life-threatening condition is most commonly seen in hematologic cancers but is sometimes described in solid tumors such as germ cell tumors (GCTs). The objective of this study is to investigate the clinical characteristics and outcomes of TLS in GCTs.




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Tuesday, March 26, 2019

Lupine Publishers-Urology open access journals



One or two years before I were considering the test of culture and sensitivity C/S in all specimens including urine is the optimal test or the last measure act in reaching the diagnosis for any. Recently this idea had gone away completely not due to the unknown extent of false negative and positive activity of the antibiotics due to vivo and vitro affairs. It is due to a fact that the revealed bacteria are not the point of our mystery especially in chronic repetitive urinary tract infection which may end in renal failure. The bacteria mentioned in the result forma or paper are what I term them as ‘’ Bad face or Quarrelsome face’’ this means if someone with this adjective is a person who is sent by someone to another someone to e.g. collect a post-due dept the owner failed to have it in usual fashion, or better when a gang boss is behind the jail bars send his outside guys to perform actions planed by him. This later example is the most correct description to the fact I want to reach which is the bacteria in the C/S result are the extra-cellular bacteria ECB where as the real problem confined in the depth of the cells where the intra-cellular bacteria ICB reside. The cells of urinary tract lining or underneath.




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Friday, March 8, 2019

Lupine Publishers-Open Journal of Nephrology



Benign prostatic hyperplasia (BPH) is an internationally important health problem of the man, particularly in developed countries. The aim of this exploratory study was to evaluate whether significant changes in the levels of Zn and some other trace elements of prostatic fluid exist in the hyperplastic prostate.




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Wednesday, November 28, 2018

Prevalence and Risk Factors of Post-Transplantation Diabetes Mellitus in Patients after Kidney Allotransplantation in Moscow: (JUNS)-Lupine publishers



Purpose:To find out the prevalence, and the risk factors conducive to the development of post-transplantation diabetes mellitus (PTDM) after kidney allotransplantation (KAT).
Methods: The medical histories of 146 recipients of kidney allotransplants received between 1989 and 2014 were reviewed in retrospect. Diabetes mellitus diagnosed before KAT was a criterion for exclusion from the study. Analysed as risk factors were: sex, age, KAT time, and the use of glycocorticoids (GCs), tacrolimus (Tc), and/or cyclosporine A (CcA). The veritability of their influence was assessed using the step-wise linear regression analysis method.
Results: The recipients’ average age was 42.9 +/- 20.2 (х±σ) years at the time of the study. PTDM prevalence in the general group was 21.9% (n=32). Age and the use of calcineurin inhibitors (CNIs) and GCs had the greatest impact on PTDM development  (р=0,01).


https://www.lupinepublishers.com/urology-nephrology-journal/pdf/JUNS.MS.ID.000108.pdf

https://www.lupinepublishers.com/urology-nephrology-journal/abstracts/prevalence-and-risk-factors-of-post-transplantation-diabetes-mellitus-in-patients-after-kidney-allotransplantation-in-moscow.ID.000108.php

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Thursday, November 15, 2018

Clinico-Functional Characteristics of Left Ventricular Dysfunction in Patients with Glomerulopathies and Their Relationship to Morphological Changes in The Kidneys: (JUNS)-Lupine publishers



Clinico-Functional Characteristics of Left Ventricular Dysfunction in Patients with Glomerulopathies and Their Relationship to Morphological Changes in The Kidneys by Aiypova Dinara in Journal of Urology & Nephrology Studies in Lupine publishers

Purpose:To study the possible association of cardiac function with morphological changes of the kidneys in glomerulopathies.
Materials and Methods: 55 patients with GP were examined (32 men, 23 women) aged from 17 to 58 (on the average 32.76 ±10.3) years. Given the high prevalence left ventricular systolic diastolic dysfunction in patients with GP with impaired renal function,analyzed the data of patients with CKD stages 1-3. The mean GFR was 87.92 ± 28.2 ml / min / 1.73 m2. Histology, immunofluorescence and electron microscopic method of investigation were used in the study of nephrobiopsy data.

https://www.lupinepublishers.com/urology-nephrology-journal/fulltext/clinico-functional-characteristics-of-left-ventricular-dysfunction-in-patients-with-glomerulopathies-and-their-relationship-to-morphological-changes-in-the-kidneys.ID.000105.php

https://www.lupinepublishers.com/urology-nephrology-journal/pdf/JUNS.MS.ID.000105.pdf

https://www.lupinepublishers.com/urology-nephrology-journal/abstracts/clinico-functional-characteristics-of-left-ventricular-dysfunction-in-patients-with-glomerulopathies-and-their-relationship-to-morphological-changes-in-the-kidneys.ID.000105.php

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Radiology; USG and Colour Doppler of Post Renal Transplant Complications

  Abstract Kidney transplant is the treatment of choice for patients with end-stage renal disease. Kidney transplant offers better...