Wednesday, November 28, 2018

Prevalence and Risk Factors of Post-Transplantation Diabetes Mellitus in Patients after Kidney Allotransplantation in Moscow: (JUNS)-Lupine publishers



Purpose:To find out the prevalence, and the risk factors conducive to the development of post-transplantation diabetes mellitus (PTDM) after kidney allotransplantation (KAT).
Methods: The medical histories of 146 recipients of kidney allotransplants received between 1989 and 2014 were reviewed in retrospect. Diabetes mellitus diagnosed before KAT was a criterion for exclusion from the study. Analysed as risk factors were: sex, age, KAT time, and the use of glycocorticoids (GCs), tacrolimus (Tc), and/or cyclosporine A (CcA). The veritability of their influence was assessed using the step-wise linear regression analysis method.
Results: The recipients’ average age was 42.9 +/- 20.2 (х±σ) years at the time of the study. PTDM prevalence in the general group was 21.9% (n=32). Age and the use of calcineurin inhibitors (CNIs) and GCs had the greatest impact on PTDM development  (р=0,01).


https://www.lupinepublishers.com/urology-nephrology-journal/pdf/JUNS.MS.ID.000108.pdf

https://www.lupinepublishers.com/urology-nephrology-journal/abstracts/prevalence-and-risk-factors-of-post-transplantation-diabetes-mellitus-in-patients-after-kidney-allotransplantation-in-moscow.ID.000108.php

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