Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Antagonists on Residual Renal Function Preservation in Peritoneal Dialysis Patients by Reyes Marin Fernando Arturo in Journal of Urology & Nephrology Studies in Lupine Publishers.
Angiotensin-converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARBs) are recommended in peritoneal dialysis (PD) patients for hypertension or heart failure control [1] Angiotensin II (AII) is an important factor in the development of renal fibrosis due to its hemodynamic effects on glomeruli and stimulation of extracellular matrix proteins synthesis, mediated by TGF b [2]. This may explain why treatment with ACEi and ARBs is renoprotective in patients with diabetic and non-diabetic nephropathy.
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